24 August 2010, 03:42 PM

• August update complete - 99 additional genomes added.

22 July 2010, 12:29 PM

• Long awaited MiST2 update completed. This update not only includes recently released genomes but also an updated list of signaling domain models and Pfam 24 models.
• There is currently a bug in the PHP server code that incorrectly renders the labels for the signal transduction profile graph. This will be fixed when the administrators update to the next stable PHP release.
• If you experience issues accessing the database, please contact us and let us know.

10 November 2009, 09:29 AM

• The MiST2 manuscript has been officially published: Abstract | Full text | PDF

08 October 2009, 10:34 AM

• Manuscript describing MiST2 has been accepted for publication in the upcoming NAR database issue!!
• Due to limited hardware resources, performing queries (especially against all genomes) is particuarly slow and may result in an internal error page. In the next couple months, we will migrate MiST2 to a dedicated server. This should substantially improve the performance and usability of this site. Thanks for your patience while we make this transition.
• Minor changes: Refseq gene name now displayed alongside all lists of proteins, added missing CheV classification.

28 September 2009, 09:37 AM

• Numerous bug fixes; finished help section last Friday evening.
• Significantly improved the search times (especially when searching the domain architecture). See the search help section to learn how to effectively query MiST2.

19 September 2009, 08:13 AM

• Added another 88 draft genomes and their predicted signal transduction repertoire.
• Currently, the help section is unfinished, yet this should be done by the end of next week.

10 September 2009, 12:29 PM

• MiST2 website launch! MiST2 is the second-generation version of the popular MiST database and provides up to date information on microbial signal transduction via a completely revamped user interface. Along with the full complement of complete genomes, MiST2 now also includes draft genomes.
• Advanced features include ECF prediction, chemotaxis and two-component classification, neighboring two-component proteins, sophisticated taxonomy browser, powerful search capabilities, advanced chromosome visualization and navigation, gene cart, and more.
• Novel genomes will be added monthly and we are in the process of integrating metagenomic sequence data.