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Genome summary

Organism Clostridium difficile R20291
Taxonomy Bacteria, Firmicutes, Clostridia, Clostridiales, Clostridiaceae, Clostridium
Size 4.2 Mbp (4,191,339 bp)
Status Complete
Replicons 1
Genes 3,567
Proteins 3,507
GC content 28.8%
Gram stain +
Shape Rod
Arrangement Singles, Pairs, Chains
Motile Yes
Habitat Multiple
Oxygen requirement Anaerobic
Salinity
Temperature range Mesophilic
Pathogenic Yes: Human
Disease Antibiotic-associated diarrhea and pseudomembraneous colitis

Signal Transduction Profile*

94 Transmitter domain(s)55 Receiver domain(s)13 Enzymatic domain(s)2 Protein-protein interaction domain(s)52 Small-molecule binding domain(s)1 Unknown domain(s)49 c-di-GMP turnover domain(s)295 DNA-binding domain(s)2 Hydrolase domain(s)2 Other domain(s)2 Phosphatase domain(s)1 Protein kinase domain(s)2 RNA-binding domain(s)10 Chemotaxis domain(s)

* Note: Chart based on domain counts (details)

Genomic distribution of signal transduction proteins by replicon

Major modes

Two-component
Accession Replicon Size (Mbp) One-component HK HHK RR HRR Other Chemotaxis * ECF Other Total
NC_013316 complete genome 4.19 260 52   55     8   3 378

* Note: Chemotaxis is a specialized form of two-component systems (details)

Chemotaxis

Accession Replicon Size (Mbp) MCP CheW CheA CheR CheB CheCX CheV CheD CheZ Other Total
NC_013316 complete genome 4.19 1 2 1 1 1 1   1     8

Neighboring two-component genes

Amount Colocated with non 2CG
Classical 40 27
Hybrid
Complex 1  
Orphan 24 16
Total 65 43
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