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What is MiST?

The Microbial Signal Transduction database contains the signal transduction proteins for bacterial and archaeal genomes (2,756 complete and 5,181 draft). These are identified using various domain profiles that directly or indirectly implicate a particular protein in participating in signal transduction.

Latest news

3 September 2013

  • In v2.2, the protein ids have changed. We are working on mapping the old ids to the new ids. Until this is complete, please use the previous version, http://v2-1.mistdb.com if you need to work with the old ids.
  • An alternative, more stable approach is to only store references to sequences using the gene locus.

26 August 2013

  • New version 2.2 - badly needed genome update; majority of new genomes are incomplete. Many genomes available for various strains of the same species.
  • Minor usability improvements (e.g. the list of genomes and the taxonomy browser is much more interactive and dynamic.)
  • No more genome metadata (phenotype, gram-stain, disease, etc.); NCBI no longer provides this information in an easily accessible format.

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Citing MiST

If you use information from the MiST database in your research, please cite:

Definitions of microbial signal transduction implemented in MiST are described in:

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Genomic distribution of signal transduction proteins

Genomes One-component Two-component Chemotaxis * ECF
Bacteria Complete 2,588 445,964 143,673 32,572 15,613
Bacteria Draft 5,091 962,876 271,862 55,914 23,091
Archaea Complete 165 11,769 2,516 980 0
Archaea Draft 90 11,586 3,156 1,296 0
Total 7,937 1,433,014 421,394 90,807 38,707

Champion genomes:

* Note: Chemotaxis is a specialized form of two-component systems (details)

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